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Meta-Analysis of Treatment Methods for Poststroke Cognitive Impairment: A Network Analysis of Various Interventions.

Brain and behaviorยทJanuary 2026ยทHuainan Li, Zhiqiang Zhao, Peng Qiao et al.
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Key Finding

Acupuncture demonstrated significant efficacy for treating poststroke cognitive impairment, with Baduanjin exercise and transcranial direct current stimulation ranking highest among seven interventions compared in this network meta-analysis of 904 patients.

What This Means For You

Cognitive problems after stroke are common and can significantly affect recovery and daily life. Researchers analyzed 11 studies involving 904 stroke survivors to compare different treatments for improving thinking and memory skills after stroke. The treatments evaluated included acupuncture, brain stimulation techniques, traditional Chinese exercises called Baduanjin, ultrasound brain stimulation, aerobic exercise, a Chinese herbal formula, and standard cognitive training exercises. All interventions showed some benefit for improving cognitive function compared to cognitive training alone. Traditional Baduanjin exercise and a brain stimulation method called transcranial direct current stimulation (tDCS) ranked as the most effective approaches. Acupuncture also demonstrated positive effects for post-stroke cognitive impairment as part of this comprehensive comparison. These findings are encouraging because they show that non-drug approaches, including acupuncture and mind-body practices, may help stroke survivors regain mental clarity and cognitive abilities. The results suggest that acupuncture could be a valuable option for people experiencing memory, attention, or thinking difficulties after a stroke, particularly when combined with other rehabilitation strategies. While more large-scale studies are still needed, this analysis provides evidence that acupuncture and other complementary therapies deserve consideration as part of a comprehensive stroke recovery program. If you're considering acupuncture for post-stroke cognitive issues, seek treatment from a licensed acupuncturist experienced in neurological rehabilitation.

Clinical Notes for Practitioners

This network meta-analysis of 11 RCTs (n=904) systematically compared seven interventions for poststroke cognitive impairment: transcranial direct current stimulation, acupuncture, Baduanjin exercise, transcranial ultrasound stimulation, moderate-intensity aerobic exercise, modified Suanzaoren decoction, and cognitive training (control). Network analysis revealed all interventions demonstrated efficacy compared to cognitive training alone, with Baduanjin exercise and tDCS ranking highest for cognitive function improvement. Acupuncture showed significant benefit as a standalone intervention within the treatment network. No significant publication bias was detected. Clinical implications suggest integrating acupuncture into multimodal PSCI rehabilitation protocols warrants consideration, particularly for patients seeking non-pharmacological approaches. The analysis supports acupuncture's role in neurological recovery, though the authors acknowledge limitations including relatively small sample sizes and call for additional large-scale RCTs. These findings provide evidence-based support for recommending acupuncture as part of comprehensive post-stroke cognitive rehabilitation strategies.

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