Exploration of Acupoint Compatibility Patterns in Acupuncture Treatment for Infertility Based on Data Mining.

Researchers analyzed 220 acupuncture treatment protocols from published studies to identify the most commonly used acupuncture points for treating three types of infertility: polycystic ovary syndrome-related infertility, diminished ovarian reserve, and unexplained infertility. Using advanced data analysis techniques, they examined patterns in how acupuncture practitioners select and combine points when treating fertility issues. The study identified 92 different acupuncture points used across all treatments, with a total of 3,653 individual point applications. The three most frequently selected points were Guanyuan (CV4, located on the lower abdomen), Sanyinjiao (SP6, on the inner ankle), and Zigong (EX-CA1, a special point near the lower abdomen). The analysis revealed that practitioners most commonly used points along the Conception Vessel meridian, the Spleen meridian, and the Stomach meridian. The research identified a core group of 15 acupuncture points that work synergistically together, with the overall treatment strategy focusing on regulating the body's reproductive channels and harmonizing qi and blood flow. These findings help explain why certain point combinations are favored in clinical practice and provide evidence-based guidance for acupuncture protocols targeting infertility. For patients considering acupuncture for fertility support, this research validates commonly used treatment approaches and highlights the importance of comprehensive protocols that address multiple aspects of reproductive health. If you're considering acupuncture for fertility concerns, seek treatment from a licensed acupuncturist with specialized training in reproductive health.

This data mining study analyzed 220 RCT prescriptions for acupuncture treatment of infertility (polycystic ovary syndrome-related, diminished ovarian reserve, and unexplained infertility) retrieved from eight databases through September 2024. Analysis identified 92 acupoints with 3,653 total applications. Highest frequency points were Guanyuan (CV4), Sanyinjiao (SP6), and Zigong (EX-CA1). Meridian distribution favored Conception Vessel, Spleen, and Stomach channels. Network analysis using Cytoscape revealed a 15-point core acupoint group including CV4, SP6, ST36, EX-CA1, CV6, GV20, SP10, BL23, BL18, ST29, CV3, LR3, KI3, CV12, and ST25. Specific point categories most utilized were Front Mu points, Five-shu points, and Yuan-primary points. The therapeutic principle centered on regulating Chong and Ren vessels and harmonizing qi-blood. Clinical takeaway: This evidence-based analysis validates traditional point selection strategies and provides systematic guidance for optimizing acupoint combinations in fertility treatment protocols.