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Effects of 36.5 Hz pulsed LASER acupuncture on pain and disease impact in fibromyalgia patients: A pilot randomized clinical trial.

Clinical rheumatology·November 2025·Rosana Aparecida De Lima, Érika Almeida Boggiss, Rhaynara Coelho Rosário et al.
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Key Finding

Laser acupuncture at 36.5 Hz pulsed frequency applied to Ryodoraku points significantly reduced pain intensity and fibromyalgia impact with large effect sizes (2.07-2.76) compared to education alone.

What This Means For You

Fibromyalgia is a challenging condition that causes widespread pain and significantly affects daily life. Researchers recently studied whether a specific type of laser acupuncture could help people with fibromyalgia manage their pain and improve their quality of life.

In this small study, 20 people with fibromyalgia between ages 40 and 78 were divided into two groups. One group received an educational lecture about fibromyalgia, while the other group received laser acupuncture treatment twice weekly for three weeks. The researchers used a special pulsed laser set at 36.5 Hz frequency, applied to specific points identified through Ryodoraku electrodiagnostic assessment—a method that helps locate optimal acupuncture points.

The results were encouraging. People who received laser acupuncture experienced significant improvements compared to the education-only group. They reported lower pain levels, fewer widespread pain symptoms, reduced severity of fibromyalgia symptoms overall, and less impact of the condition on their daily functioning. The effect sizes were large, meaning the differences between groups were substantial and clinically meaningful.

This pilot study suggests that pulsed laser acupuncture at this specific frequency may be a helpful treatment option for fibromyalgia patients struggling with pain and disability. Unlike traditional needle acupuncture, laser acupuncture is non-invasive and painless, which may appeal to those sensitive to needles. However, this was a small preliminary study, so larger research trials are needed to confirm these findings.

If you're considering laser acupuncture for fibromyalgia, seek a qualified acupuncturist with specific training and equipment in laser therapy techniques.

Clinical Notes for Practitioners

This pilot randomized controlled trial (n=20, ages 40-78) investigated 36.5 Hz pulsed laser acupuncture applied to Ryodoraku electrodiagnostic points in fibromyalgia syndrome patients. The experimental group (n=10) received biweekly treatments for three weeks, while controls (n=10) received educational lectures only.

Results demonstrated statistically significant improvements in the laser acupuncture group across all outcome measures: Pain Numeric Rating Scale (effect size=2.07, power=0.99), Generalized Pain Index (effect size=1.88, power=0.97), Symptom Severity Scale (effect size=2.55, power=0.99), and Fibromyalgia Impact Questionnaire (effect size=2.76, power=0.99). All comparisons showed p<0.05.

Clinical Takeaway: Pulsed laser acupuncture at 36.5 Hz frequency, when applied to Ryodoraku-identified points, produced large effect sizes for pain reduction and functional improvement in fibromyalgia patients. The high statistical power and substantial effect sizes suggest clinical relevance, though larger confirmatory trials are warranted given the pilot study design.

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