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Effect of single acupoint and acupoints compatibility on PSQI in patients with primary insomnia: A randomized controlled clinical trial.

Medicine·November 2025·Di Wu, Xiao-Na Liu, Xin Jia et al.
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Key Finding

Acupoint combination therapy achieved an 86.67% efficacy rate for primary insomnia compared to 66.67% with single-point treatment, with superior long-term outcomes.

What This Means For You

Researchers in China compared two different acupuncture approaches for treating primary insomnia—a common sleep disorder where people have difficulty falling or staying asleep without an underlying medical cause. The study involved 60 patients who were randomly assigned to receive either single-point acupuncture or a combination of multiple acupuncture points. The single-point group received electroacupuncture at Shenmen (HT 7), a point on the wrist traditionally used for calming the mind. The combination group received treatment at a set of points called "Sancai," which uses multiple locations working together. Both groups received their assigned treatments over a specific period, and researchers measured sleep quality using the Pittsburgh Sleep Quality Index (PSQI), a standard questionnaire that assesses various aspects of sleep.

The results showed that both approaches improved sleep quality, but the combination point treatment was significantly more effective. The success rate was 86.67% for the combination group compared to 66.67% for the single-point group. Patients receiving the combination treatment showed greater improvements in their overall PSQI scores both immediately after treatment and during follow-up visits. The study suggests that the combination approach not only worked better initially but also maintained its benefits over time.

For patients considering acupuncture for insomnia, this research suggests that treatment using multiple coordinated acupuncture points may provide better and longer-lasting sleep improvements than single-point treatments. If you're interested in acupuncture for sleep problems, seek care from a licensed acupuncturist trained in traditional Chinese medicine theory.

Clinical Notes for Practitioners

This randomized controlled trial evaluated treatment efficacy for primary insomnia comparing single-point electroacupuncture versus point combination therapy. Sixty patients were randomized into two groups (n=30 each): single-point treatment at Shenmen (HT 7) versus "Sancai" point combination. Primary outcome measure was the Pittsburgh Sleep Quality Index (PSQI). The acupoint combination group demonstrated superior efficacy with an 86.67% response rate versus 66.67% in the single-point group. Statistically significant differences in total PSQI scores were observed between groups post-treatment and at follow-up, favoring the combination group. Both interventions proved effective for primary insomnia, but the combination approach demonstrated superior immediate outcomes and sustained long-term benefits. Clinical implication: Multi-point protocols following traditional acupoint compatibility theory may optimize treatment outcomes for primary insomnia compared to single-point approaches, with enhanced durability of therapeutic effects.

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