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Comparison of the efficacy of acupoint stimulation therapy in the treatment of pain in musculoskeletal diseases: A network meta-analysis based on randomized controlled trials.

Journal of back and musculoskeletal rehabilitationยทJanuary 2026ยทZiwei Liu, Zedong Cheng, Kaixuan Zhang et al.
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Key Finding

Moxibustion was most effective for non-surgical musculoskeletal pain (SUCRA=90.26%), while traditional acupuncture was optimal for post-operative orthopedic patients (SUCRA=76.99%).

What This Means For You

Researchers conducted a comprehensive analysis comparing different acupuncture-related treatments for musculoskeletal pain, which includes conditions affecting bones, joints, and muscles. The study examined four types of acupoint therapies: traditional acupuncture (using needles), electroacupuncture (needles with electrical stimulation), moxibustion (burning herbs near the skin), and acupressure (applying pressure without needles). By analyzing data from multiple randomized controlled trials across eight major medical databases, researchers found that different techniques work best for different situations. For patients recovering from orthopedic surgery, traditional acupuncture was most effective at reducing pain scores and had the best safety profile with fewer side effects. For patients with musculoskeletal pain who did not have surgery, moxibustion proved most effective at decreasing pain levels. Acupressure was identified as the most effective overall therapeutic method. The study confirms that acupoint therapies are safe, effective, and cause no significant side effects for managing orthopedic pain. This research is important because it helps both patients and healthcare providers choose the most appropriate acupoint therapy based on individual circumstances. Rather than viewing all acupuncture techniques as interchangeable, this evidence suggests that treatment should be tailored to whether the patient has undergone surgery or is managing chronic musculoskeletal conditions. If you're considering acupoint therapy for musculoskeletal pain, consult with a licensed acupuncturist or qualified practitioner who can recommend the most appropriate technique for your specific condition.

Clinical Notes for Practitioners

This network meta-analysis evaluated the comparative efficacy of acupuncture (AP), electroacupuncture (EA), moxibustion, and acupressure for musculoskeletal pain management. Researchers systematically searched eight databases for randomized controlled trials, assessing interventions using Visual Analogue Scale (VAS) scores, safety profiles, and overall effectiveness. Quality assessment utilized the Cochrane Risk of Bias Tool, with SUCRA values quantifying intervention rankings through Bayesian random-effects modeling. Key findings indicate treatment selection should be differentiated by surgical status. For post-operative orthopedic patients, AP demonstrated optimal pain reduction (SUCRA=76.99%) and superior safety (SUCRA=83.73%). For non-surgical musculoskeletal pain, moxibustion proved most effective (SUCRA=90.26%; overall SUCRA=94.84%). Acupressure ranked highest for overall therapeutic effectiveness (SUCRA=77.93%). Clinical implications support evidence-based, condition-specific acupoint therapy selection rather than undifferentiated application. The study confirms acupoint modalities offer safe, effective analgesia for orthopedic populations, with treatment protocols appropriately matched to surgical versus conservative management contexts optimizing clinical outcomes.

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