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Comparison of the clinical efficacy of different acupuncture methods in the treatment of post-stroke central facial paralysis-a network meta-analysis based on randomized controlled trials.

Frontiers in neurologyยทMarch 2026ยทJuanshu Cao, Hang Xing, Wenlong Hu et al.
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Key Finding

Botulinum toxin type A combined with acupuncture showed the highest efficacy for improving facial disability index (SUCRA=0.90) in post-stroke central facial paralysis patients.

What This Means For You

Researchers analyzed 22 studies involving 1,888 stroke patients to compare different acupuncture methods for treating facial paralysis that occurs after a stroke. Central facial paralysis is a common complication that affects one side of the face, making it difficult to smile, close the eye, or control facial movements, significantly impacting quality of life.

The study compared eight different acupuncture approaches, including traditional acupuncture, scalp acupuncture, fire needling, and various combination treatments. Researchers evaluated both objective improvement rates and patients' own assessments of facial function using standardized scales.

Key findings showed that different acupuncture methods offered distinct advantages. When combined with conventional medical treatment or traditional Chinese medicine, acupuncture showed the strongest results for overall improvement. Fire needle therapy and scalp acupuncture performed particularly well using traditional Chinese medicine assessment criteria. For improving patients' day-to-day facial function and quality of life, combining botulinum toxin (Botox) with acupuncture showed the most promising results.

The most commonly used acupuncture points across successful treatments included Hegu (on the hand), Dicang (near the mouth), and Jiache (along the jaw). The analysis found low variation between studies and approximately 70% of the evidence was considered moderate to high quality, lending credibility to the findings.

This research supports acupuncture as a safe and cost-effective complementary treatment option for post-stroke facial paralysis. The study suggests that acupuncture therapy can be tailored to individual patient needs, with different techniques offering specific benefits. If you're considering acupuncture for post-stroke facial paralysis, consult with a licensed acupuncturist experienced in treating neurological conditions.

Clinical Notes for Practitioners

This network meta-analysis of 22 RCTs (n=1,888) compared eight acupuncture interventions for post-stroke central facial paralysis using total effective rate (TER) and facial disability index (FDI) as primary outcomes. Analysis was stratified by assessment criteria (House-Brackmann vs. TCM standards).

Using HB criteria (9 studies), acupuncture combined with conventional treatment ranked highest (SUCRA=0.84), followed by acupuncture with TCM (SUCRA=0.73) and penetrating needling with moxibustion (SUCRA=0.68). Under TCM criteria (10 studies), fire needle (SUCRA=0.82), acupuncture with TCM (SUCRA=0.79), and scalp acupuncture (SUCRA=0.78) showed superior efficacy.

For FDI improvement (15 studies), botulinum toxin A combined with acupuncture demonstrated optimal results (SUCRA=0.90), followed by cupping with acupuncture (SUCRA=0.81). Core point selection centered on Hegu, Dicang, and Jiache. Approximately 70% of evidence quality was moderate or higher. Low heterogeneity and no publication bias were detected.

Clinical takeaway: Acupuncture modality selection should be individualized based on assessment criteria and treatment goals, with combination approaches showing enhanced efficacy over monotherapy.

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