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Comparative effectiveness and safety of acupuncture treatments for primary insomnia: a systematic review and network meta-analysis of randomized trial.

Frontiers in neurologyยทMarch 2026ยทTing Fang, Xinrui Cao, Lin Liu et al.
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Key Finding

Multiple acupuncture modalities including abdominal acupuncture, standard acupuncture, and catgut embedding significantly reduced sleep quality scores compared to conventional medication, with adverse events occurring in only 5.59% of cases.

What This Means For You

Researchers analyzed 80 studies involving nearly 8,000 patients to compare different acupuncture techniques for treating primary insomnia. The study examined how various acupuncture methods performed against conventional sleep medications, fake acupuncture treatments, and each other. The results showed that several acupuncture techniques significantly improved sleep quality compared to standard medications. Specifically, abdominal acupuncture, traditional acupuncture, and catgut embedding (a technique where absorbable thread is inserted at acupuncture points) all reduced Pittsburgh Sleep Quality Index scores more effectively than medication in the short term. For long-term improvement, warm acupuncture outperformed traditional acupuncture. Beyond sleep quality, acupuncture also helped reduce anxiety and depression symptoms associated with insomnia. Importantly, acupuncture and catgut embedding showed better clinical effectiveness rates than conventional medications. Safety analysis revealed that adverse events were rare, occurring in only 5.59% of cases, with no significant safety differences between treatments. Wrist-ankle acupuncture appeared to have the best safety profile. While no single acupuncture method emerged as superior for all outcomes, abdominal acupuncture, catgut embedding, electroacupuncture, and wrist-ankle acupuncture ranked highest for various measures. The study authors noted that more research with longer follow-up periods is needed to confirm these findings. For patients struggling with primary insomnia who prefer non-medication options, these results suggest acupuncture offers a safe and effective alternative worth discussing with healthcare providers. If considering acupuncture for insomnia, seek a qualified, licensed acupuncturist experienced in treating sleep disorders.

Clinical Notes for Practitioners

This Bayesian network meta-analysis of 80 RCTs (n=7,791) compared acupuncture modalities against conventional medication and sham acupuncture for primary insomnia. Quality assessment using RoB 2.0 showed 60% low risk of bias. Short-term PSQI outcomes demonstrated significant superiority over medication for abdominal acupuncture (WMD -3.73; 95% CrI [-6.88, -0.55]), standard acupuncture (WMD -1.96; 95% CrI [-2.64, -1.27]), and catgut embedding (WMD -3.08; 95% CrI [-5.18, -0.93]). Warm acupuncture showed superior long-term PSQI reduction versus standard acupuncture (WMD -2.55; 95% CrI [-4.88, -0.21]). Acupuncture significantly reduced anxiety (SMD -2.0) and depression (SMD -1.52) compared to sham. Clinical efficacy rates favored acupuncture (RR 1.19) and catgut embedding (RR 1.25) over medication. Adverse events occurred in 5.59% of cases with no significant differences between modalities. SUCRA rankings indicated abdominal acupuncture, catgut embedding, electroacupuncture, and wrist-ankle acupuncture demonstrated relative advantages. Clinical application should consider individual patient presentation, though publication bias and protocol heterogeneity warrant cautious interpretation.

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