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[Clinical dose-effect study of acupuncture at Lianquan (CV23) with different frequencies of twirling manipulation for post-ischemic stroke aphasia].

Zhongguo zhen jiu = Chinese acupuncture & moxibustionยทApril 2026ยทJunjie Chen, Hailun Jiang, Shizhe Deng et al.
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Key Finding

Low-frequency twirling manipulation (60 times/min) at acupoint Lianquan (CV23) achieved 82.35% effectiveness in treating post-ischemic stroke aphasia, significantly superior to high-frequency manipulation (71.88%) and sham acupuncture (54.55%).

What This Means For You

Researchers studied whether different speeds of needle manipulation during acupuncture could help stroke patients recover their language abilities. The study included 105 patients who experienced aphasia (difficulty speaking or understanding language) after an ischemic stroke. Patients were divided into three groups: one received acupuncture at the Lianquan point (located on the front of the neck) with slow needle twirling (60 times per minute), another received fast twirling (120 times per minute), and a control group received sham acupuncture at non-traditional points. All patients also received standard stroke treatment. The treatments were given daily, five times per week, for six weeks.

The results showed that both acupuncture groups improved more than the sham group, but slow twirling produced the best outcomes. Patients receiving slow-twirling acupuncture showed greater improvements in their ability to speak spontaneously, understand others, and communicate in daily life. They also had better overall language scores and quality of life measures. The slow-twirling group had an 82% effectiveness rate, compared to 72% for fast-twirling and 55% for sham acupuncture. Neurological function also improved more with the slower technique.

For stroke patients struggling with speech and language problems, this research suggests that acupuncture using slower needle manipulation at specific points may be beneficial when combined with conventional stroke rehabilitation. The technique appears to support recovery of both expressive and receptive language abilities while improving overall quality of life. If considering acupuncture for post-stroke aphasia, seek a licensed acupuncturist with experience in neurological rehabilitation.

Clinical Notes for Practitioners

This randomized controlled trial (n=105, 99 completed) investigated dose-effect relationships of needle manipulation frequency at CV23 for post-ischemic stroke aphasia. Patients received either low-frequency twirling (60 times/min), high-frequency twirling (120 times/min), or sham acupuncture, combined with Xingnao Kaiqiao acupuncture protocol and conventional stroke care, administered daily (5ร—/week) for six weeks. Primary outcomes included WAB, BDAE, NIHSS, and SAQOL-39 scores. The low-frequency group demonstrated superior outcomes compared to high-frequency, with significantly higher WAB-AQ scores, spontaneous speech scores, and communication scores (P<0.05), plus lower NIHSS scores. Total clinical effectiveness was 82.35% (LT), 71.88% (HT), and 54.55% (SA). Both active treatment groups significantly outperformed sham (P<0.05). Clinical takeaway: Lower frequency twirling manipulation (60 times/min) at CV23 produces more robust improvements in language function, neurological status, and quality of life than higher frequency manipulation in post-stroke aphasia rehabilitation.

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